Best Longevity Supplements for Healthy Aging, Energy & Vitality

At HormoneSynergy® / RetzlerRx™, we know that healthy aging is about more than adding years to your life—it’s about adding life to your years. Longevity supplements can support cellular health, energy production, immune resilience, and cardiovascular wellness, helping you feel your best at every age.

While no supplement guarantees a longer lifespan, research shows that anti-aging nutrients can help improve healthspan, protect against oxidative stress, and promote vitality and well-being.

Below are some of the most clinically studied supplements for healthy aging, energy, and longevity.


Resveratrol – The Anti-Aging Polyphenol

Resveratrol, found in grapes, berries, and red wine, is a potent antioxidant that may:

  • Support cardiovascular health and blood vessel function*

  • Activate longevity pathways linked to cellular health*

  • Protect against oxidative stress and inflammation*


NAD+ Precursors – NMN & Nicotinamide Riboside (NR)

Compounds like NMN and NR help increase NAD+, a molecule essential for cellular energy and repair. Benefits include:

  • Boosting mitochondrial energy production*

  • Supporting metabolic health and vitality*

  • Promoting healthy aging pathways in preclinical studies*


Coenzyme Q10 (CoQ10) – Energy & Heart Support

One of the most popular longevity supplements, CoQ10 may help:

  • Support cellular energy production*

  • Promote circulation and cardiovascular function*

  • Protect against oxidative stress*


Omega-3 Fatty Acids – Brain, Heart & Longevity Support

Omega-3s (EPA & DHA), found in fish oil, flaxseed, and walnuts, are essential for:

  • Heart and brain health support*

  • Maintaining inflammatory balance*

  • Promoting joint mobility and vitality*

Look for IFOS-certified omega-3 supplements for quality and purity.


Vitamin D – The Sunshine Vitamin

Adequate vitamin D3 supports:

  • Bone health and density*

  • Immune system balance*

  • Overall vitality and longevity*


Curcumin – Antioxidant & Inflammation Balance

Derived from turmeric, curcumin helps:

  • Combat oxidative stress*

  • Promote joint comfort and flexibility*

  • Support healthy immune balance*


Berberine & Advanced Metabolic Formulas

Used for centuries in herbal medicine, berberine supports:

  • Metabolic health & lipid balance*

  • Blood sugar regulation*

  • Cardiovascular health*

Advanced forms like Dihydroberberine (DHB) or blends with curcumin and citrus bergamot offer even greater benefits.


Glutathione – The Master Antioxidant

Glutathione plays a central role in:

  • Cellular detoxification & repair*

  • Protecting cells from oxidative damage*

  • Supporting immune function and resilience*

Liposomal or S-acetyl forms improve absorption and effectiveness.


The Bottom Line on Healthy Aging Supplements

The best results come from combining longevity supplements with:

  • A nutrient-rich diet

  • Regular physical activity

  • Restorative sleep

  • Stress management practices

For personalized recommendations, always consult your healthcare provider before starting a new supplement regimen.

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