Where is HormoneSynergy® Clinic located?

HormoneSynergy® Clinic is located in Lake Oswego, Oregon and serves patients locally in Lake Oswego and Portland while shipping supplements nationwide in the United States.

Do you offer preventive longevity medicine services?

Yes. Our clinic focuses on evidence-based preventive longevity medicine using advanced diagnostics and personalized care plans.

Do you ship supplements nationwide?

Yes. Our online store ships select supplements nationwide across the United States.

HormoneSynergy® Longevity Medicine | Preventive Care Portland

Dr. Kathryn Retzler

HormoneSynergy® Longevity Medicine is a physician-led preventive health clinic serving Portland and Lake Oswego, Oregon. We use the term longevity medicine to describe a healthspan-focused clinical approach: early disease-risk detection, hormone replacement therapy, metabolic health, preventive cardiology, and advanced diagnostics including DEXA bone density and body composition scans, carotid artery ultrasound, SECA body composition testing, CNS Vital Signs, and AI-assisted coronary CT angiography with Cleerly®.

Led by Dr. Kathryn Retzler, a nationally recognized physician with more than 25 years of clinical experience, HormoneSynergy® emphasizes evidence-informed prevention, metabolic health, cardiovascular risk reduction, hormone balance, and measurable outcomes for patients in Portland, Lake Oswego, and across the United States.

Transparency note: Longevity medicine is an emerging clinical focus, not an ABMS-recognized board specialty. We use the term to describe our preventive, systems-based approach to healthspan, metabolic risk, hormone health, cardiovascular prevention, cognition, strength, and aging-related risk assessment.

HormoneSynergy®

Preventive Medicine With a Healthspan Focus

At HormoneSynergy®, we focus on identifying risk early, measuring meaningful changes in physiology and building a physician-guided plan for long-term health. The Optimal Aging Assessment evaluates cardiovascular risk, metabolism, hormones, bone health, body composition and cognition in one integrated assessment.

Comprehensive longevity medicine does not require every available scan, genetic panel or performance test to be included for every patient. Whole-body MRI, genomic testing, VO₂ max and other specialized studies can be added when a patient’s history, risk factors or initial findings indicate that they are likely to provide useful information.

This clinically selective approach keeps comprehensive physician-led longevity medicine more accessible, while reserving additional testing for patients whose history, risk factors or initial findings indicate that it is likely to influence care.

This selective approach allows HormoneSynergy® to provide comprehensive physician-led longevity medicine without requiring every patient to pay for testing that may not change care.

Care

Concierge Longevity Medicine

HormoneSynergy® is a physician-led longevity medicine clinic in Portland, Oregon specializing in preventive cardiology, metabolic health, hormone optimization, and advanced diagnostic testing. Our approach focuses on early detection of disease risk and personalized, evidence-based prevention strategies.

01

Preventive Cardiology & Early Heart Disease Detection

Cardiovascular disease often develops silently for years before symptoms appear. With more than 25 years of clinical experience in preventive cardiology, Dr. Kathryn Retzler uses advanced imaging, vascular testing, and targeted diagnostics—including Cleerly®-enabled Coronary CT Angiography (CCTA)—to directly visualize coronary plaque and more accurately assess cardiovascular risk.

Rather than relying on indirect markers or late-stage detection, the focus is early identification, precise risk assessment, and proactive care—supporting long-term cardiovascular health and longevity.

Metabolic Health & Medical Weight Loss

Metabolic dysfunction is one of the most important drivers of long-term disease risk. We focus on insulin resistance, body composition, and sustainable weight loss through structured medical care.

GLP-1–based weight loss programs (semaglutide, tirzepatide)
Continuous glucose monitoring
Insulin resistance and metabolic optimization

03

Hormone Therapy for Men & Women

Hormones influence metabolism, cognition, muscle mass, bone density, and overall quality of life. Our approach focuses on individualized optimization based on symptoms, labs, and long-term goals.

Testosterone therapy for men and women
Bioidentical hormone replacement therapy (BHRT)
Perimenopause, menopause, and andropause care

Advanced Diagnostics

Advanced Diagnostics & Body Composition and Neurocognitive testing

Advanced diagnostics help move preventive care beyond guesswork. HormoneSynergy® uses tools such as DEXA bone density and visceral fat analysis, SECA body composition testing, CNS Vital Signs neurocognitive testing, carotid artery ultrasound, and Cleerly®-enabled coronary CT angiography when clinically appropriate.

Body Composition

DEXA Bone Density, Visceral Fat and Muscle Scan

These assessments help evaluate bone health, visceral fat, lean mass, cognitive performance, vascular risk, and early cardiometabolic changes so care can be guided by measurable data rather than symptoms alone.

Brain Health

Neurocognitive Testing

CNS Vital Signs (CNSVS) is a computerized, HIPAA-compliant neurocognitive assessment platform designed for rapid, objective, and longitudinal evaluation of brain function in patients ages 8–90. It functions as a “fitness test” for the brain, measuring key domains such as memory, processing speed, attention, and executive function. These insights help clinicians identify patterns, track changes over time, and support the evaluation of conditions including ADHD, concussion, and mild cognitive impairment within a broader longevity medicine framework.

Cellular Health

Nutrient and Cellular Health Testing

Optimal health requires adequate micronutrient status and healthy cellular function.

These nutrients influence mitochondrial function, cardiovascular health, inflammation, brain performance, and recovery.

Start your free Vitamin and Nutrient Assessment.

Vitamin D
Vitamin B12
Coenzyme Q10
Omega-3 fatty acids

Longevity Guide

Explore the HormoneSynergy® Longevity Medicine Resource Library

The HormoneSynergy® Longevity Medicine Resource Library is a free patient-education hub reflecting Dr. Kathryn Retzler’s clinical perspective and Daniel Soule’s editorial voice as Clinic Director and owner.

For patients who want to understand the science behind our approach, the Resource Library organizes our educational articles by topic, including metabolic health, preventive cardiology, hormone transitions, brain health, sleep, gut health, inflammation, food quality, environmental exposure, advanced diagnostics, and evidence-based aging.

It is designed to help patients think more clearly about healthspan, risk reduction, diagnostics, and whole-person preventive care without relying on hype, trends, or influencer medicine.

Longevity Medicine Resource Library

RetzlerRx®

Supplements in Longevity Medicine

HormoneSynergy® uses supplements as clinical tools, not as a substitute for medicine. Dr. Kathryn Retzler may recommend targeted nutritional support for metabolic health, cardiovascular health, brain health, hormone health, gut health and healthy aging based on the individual patient’s needs.

Recommendations may include RetzlerRx® physician-formulated supplements and selected professional products from Designs for Health®, Metagenics®, Xymogen®, Researched Nutritionals® and Microbiome Labs® when clinically appropriate.

Medicine, not marketing. More supplements do not necessarily mean better medicine.

Explore Physician-Guided Supplements

RetzlerRx® physician-formulated supplements

HormoneSynergy® Clinic

Google Reviews

★★★★★

I have been a patient of Dr. Kathryn Retzler’s for the past 12 years, and I can honestly say that she has had an incredible impact on my life. She is so much more than an exceptional doctor—she is someone who truly understands the …

★★★★★

Dr. Kathryn Retzler and the team at HormoneSynergy Clinic are an incredible value to our community. What sets them apart is how well they explain things, they take the time to walk you through your labs and your options so you actually …

★★★★★

I have been trusting Dr. Retzler and her team with my health care, (blood work) for about the last eight years. They are very efficient with scheduling appointments and Dr. Retzler is very thorough when answering my questions. I would recommend Hormone Synergy Clinic.

★★★★★

Dr. Retzler is a kind, compassionate care provider who is always up on the latest research with regard hormones, aging and longevity. I have been a patient for many years and plan to continue!

★★★★★

Helpful, friendly and competent staff. Dr.R is very knowledgeable and up to date with latest research, developments and health management strategies. Blood work tests are comprehensive and complete to determine health status on my body …

★★★★★

I had a follow-up appointment today to review Blood Test Results. Dr. Retzler reviewed & explained my test results in detail and advised recommended prescription changes. Because I mentioned some weight gain, she immediately performed a …

★★★★★

Absolutely the best company in Portland Oregon for Hormone Therapy. I am also loving all their products that they have created. Perfect balance in my life.

★★★★★

Always very professional……close monitoring of hormone and blood work….been a patient for 12ys

★★★★★

I have been a patient of Dr. Kathryn Retzler’s for the past 12 years, and I can honestly say that she has had an incredible impact on my life. She is so much more than an exceptional doctor—she is someone who truly understands the …

★★★★★

Dr. Kathryn Retzler and the team at HormoneSynergy Clinic are an incredible value to our community. What sets them apart is how well they explain things, they take the time to walk you through your labs and your options so you actually …

★★★★★

I have been trusting Dr. Retzler and her team with my health care, (blood work) for about the last eight years. They are very efficient with scheduling appointments and Dr. Retzler is very thorough when answering my questions. I would recommend Hormone Synergy Clinic.

★★★★★

Dr. Retzler is a kind, compassionate care provider who is always up on the latest research with regard hormones, aging and longevity. I have been a patient for many years and plan to continue!

★★★★★

Helpful, friendly and competent staff. Dr.R is very knowledgeable and up to date with latest research, developments and health management strategies. Blood work tests are comprehensive and complete to determine health status on my body …

★★★★★

I had a follow-up appointment today to review Blood Test Results. Dr. Retzler reviewed & explained my test results in detail and advised recommended prescription changes. Because I mentioned some weight gain, she immediately performed a …

★★★★★

Absolutely the best company in Portland Oregon for Hormone Therapy. I am also loving all their products that they have created. Perfect balance in my life.

★★★★★

Always very professional……close monitoring of hormone and blood work….been a patient for 12ys

★★★★★

I’ve been a patient here for a long time - for good reasons. Dr. Retzler is extremely competent and stays up-to-date on all pertinent research, etc. Her knowledge, interests and acumen are wide ranging. Her staff is always courteous and friendly and helpful. Dr. Retzler is my most trusted resource for medical guidance.

★★★★★

Dr. Retzler is simply the best, most informed and informative doctor I have ever been to. She has helped me navigate migraines and menopause. I cannot recommend her enough. All of her staff is fantastic and helpful as well.

★★★★★

Dr Katherine is a staple in why I was able to overcome heart issues since 2022! Brilliant woman who understands people & why the circulatory system does what it does! Strongly recommend her & her pleasant friendly staff be part of your life!

★★★★★

Dr. Retzler is one of the rare doctors that takes the time to listen and ask about how your personal life is going as well as take the time to explain things that you can understand so you can be healthier and preventive instead of just …

★★★★★

Credit for my good health over these last 25yrs plus largely belongs to Dr Retzler. Not only did she advise and explain the benefits of HRT at a time when it was …

★★★★★

Not just quantity of life, quality of life. Reclaimed my health both mentally and physically with the help of Dr. Retzler. I would recommend her to anyone!

★★★★★

Dr. Retzler and Synergy is a great Doctor. I have been a patient for over 10 years. She is very helpful and her team is great!

★★★★★

Fabulous! Knows her stuff. Has helped me stay healthy for many years. Well worth every penny.

★★★★★

I’ve been a patient here for a long time - for good reasons. Dr. Retzler is extremely competent and stays up-to-date on all pertinent research, etc. Her knowledge, interests and acumen are wide ranging. Her staff is always courteous and friendly and helpful. Dr. Retzler is my most trusted resource for medical guidance.

★★★★★

Dr. Retzler is simply the best, most informed and informative doctor I have ever been to. She has helped me navigate migraines and menopause. I cannot recommend her enough. All of her staff is fantastic and helpful as well.

★★★★★

Dr Katherine is a staple in why I was able to overcome heart issues since 2022! Brilliant woman who understands people & why the circulatory system does what it does! Strongly recommend her & her pleasant friendly staff be part of your life!

★★★★★

Dr. Retzler is one of the rare doctors that takes the time to listen and ask about how your personal life is going as well as take the time to explain things that you can understand so you can be healthier and preventive instead of just …

★★★★★

Credit for my good health over these last 25yrs plus largely belongs to Dr Retzler. Not only did she advise and explain the benefits of HRT at a time when it was …

★★★★★

Not just quantity of life, quality of life. Reclaimed my health both mentally and physically with the help of Dr. Retzler. I would recommend her to anyone!

★★★★★

Dr. Retzler and Synergy is a great Doctor. I have been a patient for over 10 years. She is very helpful and her team is great!

★★★★★

Fabulous! Knows her stuff. Has helped me stay healthy for many years. Well worth every penny.

Preventive, Metabolic & Healthspan-Focused Medicine

Preventive Medicine With a Healthspan Focus

Concierge Longevity Medicine

Preventive Cardiology & Early Heart Disease Detection

Metabolic Health & Medical Weight Loss

Hormone Therapy for Men & Women

Advanced Diagnostics & Body Composition and Neurocognitive testing

DEXA Bone Density, Visceral Fat and Muscle Scan

Neurocognitive Testing

Nutrient and Cellular Health Testing

Explore the HormoneSynergy® Longevity Medicine Resource Library

Supplements in Longevity Medicine

The HormoneSynergy® Longevity Letter

Medicine.Not Marketing.

Google Reviews

Nutrient and Cellular Health Testing