At HormoneSynergy®, we believe aging is inevitable—but how you age is not predetermined. Longevity medicine goes beyond preventing disease; it focuses on preserving energy, cognitive function, metabolic health, and overall vitality throughout life.
Led by Dr. Kathryn Retzler, a nationally recognized physician with more than 25 years of experience, HormoneSynergy® practices evidence-based preventive longevity medicine. Our approach emphasizes early risk detection, metabolic health, cardiovascular prevention, and hormone balance for patients in Portland, Lake Oswego, and nationwide.
Our philosophy is simple: detect risk early, improve function, and extend healthspan through physician-led, measurement-driven care. Using advanced diagnostics, lifestyle medicine, and targeted therapies—including hormone optimization when appropriate—we help patients restore energy, improve metabolic resilience, and reduce long-term disease risk.
We are not alternative medicine.
We do not sell immortality.
We practice real medicine focused on prevention, precision diagnostics, and measurable health outcomes.
Dr. Kathryn Retzler
Physician. Educator. Author. Consultant
"I believe many people settle for a negative definition of aging. I do not accept that aging means 'falling apart on schedule'. I have a high standard for my physical, mental and spiritual health, improving every year. I hold the same vision for my patients.
Preventive Longevity and Precision Medicine
At HormoneSynergy®, we serve individuals who want more than traditional disease management or symptom chasing. Our concierge clinic practices evidence-based preventive longevity medicine, combining advanced diagnostics, personalized prevention strategies, and select functional medicine principles to help restore energy, improve function, and extend healthspan.
Rather than treating symptoms alone, we focus on identifying the underlying drivers of aging and chronic disease using measurement-driven diagnostics, physician-guided therapies, and lifestyle strategies tailored to your physiology. By integrating clinical research in hormone optimization (when appropriate), metabolic health, cardiovascular prevention, and longevity medicine, we develop comprehensive care plans designed to help you improve measurable markers of health and live longer with greater vitality.
HormoneSynergy® / RetzlerRx® Weight Loss for Longevity Program
The HormoneSynergy® / RetzlerRx® Weight Loss for Life Program is a medically supervised, science-driven weight loss program designed to improve body composition, metabolic health, and long-term longevity.
Our comprehensive approach combines DEXA body composition analysis, physician-guided metabolic care, personalized functional medicine coaching, and targeted nutritional support with GLP-1 weight loss medications such as semaglutide and tirzepatide when appropriate.
By addressing the metabolic drivers of weight gain—including insulin resistance, body composition changes, and hormonal factors—this program helps patients achieve sustainable fat loss, improved metabolic balance, and long-term health optimization, rather than temporary or restrictive dieting results.
Cleerly® Testing - A New Standard for Cardiovascular Care
Cleerly® Heart Health Analysis uses a clinically validated, AI-powered digital care platform combined with Coronary Computed Tomography Angiography (CCTA) to help Dr. Kathryn Retzler detect and evaluate coronary artery disease and atherosclerosis at the earliest stages.
This advanced imaging technology provides detailed visualization of coronary plaque, including both calcified and non-calcified deposits, while assessing the degree of arterial narrowing (stenosis) to accurately stage and monitor cardiovascular disease progression over time.
By leveraging AI-enabled CCTA analysis, Cleerly® delivers faster, more precise, and highly personalized heart health insights—supporting a proactive, precision-based preventive cardiology strategy designed to reduce cardiovascular risk, improve long-term outcomes, and optimize longevity.
DEXA (DXA) Bone Density plus Full Body and Visceral Fat Analysis
Our Hologic® DXA Bone Density and Body Composition Analysis provides a cutting-edge, non-invasive diagnostic scan that delivers precise insights into bone health, muscle mass, and visceral fat levels—key markers of metabolic health and healthy aging.
The DXA bone density scan uses advanced low-dose X-ray technology to accurately measure bone mineral density, helping assess risk for osteoporosis, fractures, and age-related bone loss. This quick, painless test provides reliable data that supports personalized prevention and longevity strategies.
Our whole-body DXA body composition analysis evaluates muscle mass, total body fat, and visceral fat surrounding critical organs, providing insights strongly linked to cardiovascular disease risk, insulin resistance, and metabolic health.
By combining bone health evaluation with detailed body composition analysis, DXA provides a clear, data-driven picture of your metabolic and structural health, helping guide personalized strategies to improve healthspan and longevity.
Carotid Artery Ultrasound using Vasolabs® with Butterfly Ultrasound Technology
Vasolabs® Heart Disease Screenings offer an affordable, convenient, and non-invasive way to detect early signs of heart disease—with no physician referral required. Using state-of-the-art vascular ultrasound technology, Vasolabs® delivers fast, accurate, and pain-free heart health assessments designed for proactive prevention and peace of mind.
Key benefits of Vasolabs® Heart Screenings include:
- No Referrals Needed – Schedule your screening directly—no waiting or paperwork delays.
- Advanced Ultrasound Technology – Detect early signs of heart disease with the latest imaging innovations.
- Non-Invasive & Comfortable – No wires, treadmills, or needles required; just a quick, stress-free test.
- Fast Results – Receive your easy-to-read report within 48 hours via email.
- Optional Clinician Consultation – Review your results with a healthcare provider if desired.
- Quick & Affordable – The test takes just 15 minutes and costs only $249.
Take control of your heart health today. Call 503-230-7990 to schedule your Vasolabs® Heart Disease Screening.
Preventive Cardiology
Cardiovascular disease remains the leading cause of death in the United States, claiming more than 800,000 lives each year. Every 25 seconds, someone suffers a heart attack, and every minute, someone dies from cardiovascular disease. For survivors, the financial impact can also be substantial—average out-of-pocket costs following a heart attack or stroke often range from $25,000–$30,000 annually after insurance, and may increase by $100,000 or more if surgery is required.
At HormoneSynergy®, Dr. Kathryn Retzler specializes in Preventive Cardiology, bringing more than 25 years of clinical experience and advanced training through two preventive cardiology fellowships with Mark Houston, MD, through the American Academy of Anti-Aging Medicine. Her approach focuses on identifying cardiovascular risk early and implementing proactive, evidence-based strategies designed to reduce heart attack and stroke risk while supporting long-term cardiovascular health and longevity.
Take charge of your heart health before symptoms appear—because prevention saves lives and protects your future.
Bioidentical Hormone Replacement
Humans are unique in that we live many years beyond our reproductive lifespan. For many individuals, aging begins to accelerate in the mid to late 40s as hormone levels gradually decline. Because hormones influence nearly every system in the body, these changes can affect energy, metabolism, muscle mass, bone health, mood, memory, and sexual wellness.
At HormoneSynergy®, we offer Bioidentical Hormone Replacement Therapy (BHRT) using human-identical hormones designed to restore healthy physiological balance. Our physician-guided hormone optimization programs support both men and women experiencing hormone-related changes associated with aging.
Hormone optimization may help support:
• Energy and vitality for active aging
• Metabolism, muscle mass, and body composition
• Bone strength and joint health
• Mood, memory, and sexual wellness
• Skin health and overall vitality
Using a functional and preventive medicine approach, our personalized hormone replacement programs are designed to support long-term health, metabolic resilience, and healthy aging.
Testosterone Replacement Therapy
Testosterone Therapy for both men and women plays a vital role in supporting metabolic health, sexual wellness, athletic performance, and overall quality of life. As testosterone levels naturally decline with age, many individuals experience changes in energy, mood, muscle mass, and cognitive function that can affect long-term health and well-being.
At HormoneSynergy®, we offer personalized testosterone optimization programs designed to help support:
- Metabolic health and healthy body composition
- Sexual function and libido for men and women
- Athletic performance and muscle strength for active lifestyles
- Mood stability and mental clarity for emotional and cognitive wellness
- Heart health and diabetes prevention through balanced hormone support
Using a functional and integrative medicine approach, we tailor testosterone therapy to your unique health goals, helping restore vitality and optimize longevity at every stage of life.
Advanced Diagnostics & Concierge Longevity Medicine Services
At HormoneSynergy®, we combine physician-guided longevity medicine with advanced diagnostic testing designed to detect disease risk early and guide personalized prevention strategies.
• DEXA Bone Density and Body Composition Analysis
• DEXA 'Whole Body' Visceral Fat and Muscle Mass Assessment
• Carotid Artery Ultrasound Screening (CIMT / Vascular Ultrasound)
• Cleerly® AI-Enabled Coronary CT Angiography (CCTA) Analysis
• Advanced Cardiometabolic Blood Testing
• Hormone Optimization and Bioidentical Hormone Therapy
• Medical Weight Loss and GLP-1 Metabolic Therapy
• Preventive Cardiology and Cardiovascular Risk Assessment
• Cognitive Health and Brain Performance Testing
These advanced diagnostics help identify cardiovascular disease, metabolic dysfunction, hormonal imbalance, and body composition changes years before symptoms develop, enabling proactive prevention and personalized longevity care.
I’ve been Dr. Retzler’s patient for nearly 24 years, and I consider myself very fortunate to have found her. With her guidance and bioidentical hormone treatment, I’ve eased through menopause enjoying vibrant health and well-being. I feel wonderful!*
Judith Bernards
HormoneSynergy® Clinic & RetzlerRx® specialize in longevity medicine, GLP-1 weight loss, Integrative medicine, and bioidentical hormone therapy in Portland / Lake Oswego OR.
Physician-formulated nutritional supplements, shipped USA nationwide.
Non concierge services include carotid artery ultrasound, DEXA / DXA Bone Density Scans, SECA Body Composition testing and our GLP-1 Weight Loss for Longevity™ program.
© 2026 HormoneSynergy® Clinic LLC. All rights reserved.
Educational content may not be reproduced without permission.