HormoneSynergy® Longevity Medicine is a physician-led preventive health clinic in Portland, Oregon specializing in early disease detection, hormone replacement therapy, metabolic health, and advanced diagnostics including DEXA bone denisty Scans, carotid artery ultrasound, and AI-assisted coronary CT angiography (Cleerly®). Care is built on evidence-based medicine with a focus on long-term healthspan, performance, and measurable outcomes.
Led by Dr. Kathryn Retzler, a nationally recognized physician with more than 25 years of experience, HormoneSynergy® practices evidence-based preventive longevity medicine. Our approach emphasizes early risk detection, metabolic health, cardiovascular prevention, and hormone balance for patients in Portland, Lake Oswego, and nationwide.
Evidence-Based Preventive Longevity Medicine
At HormoneSynergy®, we focus on identifying risk early, optimizing physiology, and building long-term health through a structured, physician-guided approach. This is not reactive medicine. It is a proactive model designed to detect, measure, and improve the systems that drive aging, performance, and disease risk.
We serve patients in Portland, Lake Oswego, and across the United States through a combination of in-clinic diagnostics and guided care.
Preventive Cardiology & Early Heart Disease Detection
HormoneSynergy® is a physician-led longevity medicine clinic in Portland, Oregon specializing in preventive cardiology, metabolic health, hormone optimization, and advanced diagnostic testing. Our approach focuses on early detection of disease risk and personalized, evidence-based prevention strategies.
Cardiovascular disease often develops silently for years before symptoms appear. With more than 25 years of clinical experience in preventive cardiology, Dr. Kathryn Retzler uses advanced imaging, vascular testing, and targeted diagnostics—including Cleerly®-enabled Coronary CT Angiography (CCTA)—to directly visualize coronary plaque and more accurately assess cardiovascular risk.
Rather than relying on indirect markers or late-stage detection, the focus is early identification, precise risk assessment, and proactive care—supporting long-term cardiovascular health and longevity.
Metabolic Health & Medical Weight Loss
Metabolic dysfunction is one of the most important drivers of long-term disease risk. We focus on insulin resistance, body composition, and sustainable weight loss through structured medical care.
- GLP-1–based weight loss programs (semaglutide, tirzepatide)
- Continuous glucose monitoring
- Insulin resistance and metabolic optimization
Hormone Therapy for Men & Women
Hormones influence metabolism, cognition, muscle mass, bone density, and overall quality of life. Our approach focuses on individualized optimization based on symptoms, labs, and long-term goals.
- Testosterone therapy for men and women
- Bioidentical hormone replacement therapy (BHRT)
- Perimenopause, menopause, and andropause care
Advanced Diagnostics & Body Composition and Neurocognitive testing
HormoneSynergy® is a physician-led longevity medicine clinic in Portland, Oregon specializing in preventive cardiology, metabolic health, hormone optimization, and advanced diagnostic testing. Our approach focuses on early detection of disease risk and personalized, evidence-based prevention strategies.
Cardiovascular disease often develops silently for years before symptoms appear. With more than 25 years of clinical experience in preventive cardiology, Dr. Kathryn Retzler uses advanced imaging, vascular testing, and targeted diagnostics—including Cleerly®-enabled Coronary CT Angiography (CCTA)—to directly visualize coronary plaque and more accurately assess cardiovascular risk.
Rather than relying on indirect markers or late-stage detection, the focus is early identification, precise risk assessment, and proactive care—supporting long-term cardiovascular health and longevity.
Advanced Diagnostics & Concierge Longevity Medicine Services
At HormoneSynergy®, we combine physician-guided longevity medicine with advanced diagnostic testing to detect disease risk early and guide personalized prevention strategies.
Our approach integrates cardiovascular screening, body composition and metabolic testing, hormone optimization, and cognitive performance evaluation—providing a comprehensive understanding of your health before symptoms develop.
HormoneSynergy® Clinic & RetzlerRx® specialize in longevity medicine, GLP-1 weight loss, Integrative medicine, and bioidentical hormone therapy in Portland / Lake Oswego OR.
Physician-formulated nutritional supplements, shipped USA nationwide.
Non concierge services include carotid artery ultrasound, DEXA / DXA Bone Density Scans, SECA Body Composition testing and our GLP-1 Weight Loss for Longevity™ program.
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