Longevity Medicine, Functional Wellness & Anti-Aging Insights from HormoneSynergy®

Becoming a licensed naturopathic physician requires years of medical education, board examinations, and commitment. What happens after graduation is less predictable. Scope of practice varies by state, residencies are limited, professional acceptance remains uneven, and many young physicians discover that building a career also means learning how to build a business.

Metagenics has expanded collagen beyond the usual skin-and-beauty category with StayStrong+, a new line combining targeted collagen ingredients with creatine, UC-II®, vitamin D, magnesium, and connective-tissue support. The formulas are interesting, but the type of collagen and the dose still deserve a closer look.

Celebrate our 25-year partnership with Metagenics®. New customers receive 0% off their first order plus free shipping through our practitioner portal. 

Explore 20 popular Metagenics® formulas for gut health, metabolic health, inflammation balance, menopause support, stress resilience, muscle health, and healthy aging. New customers registering through the HormoneSynergy® practitioner connection can receive 20% off their first order, with the discount applied automatically and no coupon code required.

A 90-day human pilot study of Big Bold Health HTB Rejuvenate found intriguing changes in epigenetic aging, immune-cell patterns, and biological pathways associated with immune aging. The often-quoted 47% result is real, but it came from a small subgroup. Here is what the study actually found and why the larger story may be more interesting.

MegaIgG2000 is a dairy-free, serum-derived bovine immunoglobulin supplement available as a powder or capsules. Both provide 2 grams of ImmunoLin® per serving, but the powder contains slightly more IgG and allows more flexible dosing, while the capsules offer greater convenience. 

CBD and THC creams are widely sold for sore muscles, arthritis, joint stiffness, and inflammation. The biology is plausible, but the clinical evidence is much thinner than the marketing. Here is what we know about cannabinoid receptors in the skin, topical versus transdermal delivery, arthritis and neuropathic pain, muscle soreness, and why the formulation may matter as much as the cannabinoid itself.

Estradiol matters for bone, sexual function, body composition and metabolism in men. Learn why routine estrogen suppression during TRT may be unnecessary.

Low triglycerides, good insulin sensitivity, normal blood pressure, and excellent fitness are all favorable for cardiovascular health. But do they make a very high LDL-C or ApoB less important? The biology is more nuanced than either side of the cholesterol debate usually admits.

A large UK Biobank study linked long-term statin use with faster declines in grip strength and appendicular lean mass. The signal deserves attention, but the widely repeated “73% muscle loss” interpretation is wrong, and newer studies have not confirmed that statins increase sarcopenia risk.

A large 2026 prospective study found that sarcopenic obesity, the combination of excess body fat with low muscle mass and function, was associated with a 34% higher risk of dementia. The strongest and most consistent signal was not body weight. It was declining muscle strength. The findings reinforce an important longevity principle: preserving muscle while improving body composition may matter far more than simply making the number on the scale smaller.

A rising coronary artery calcium score usually sounds like worsening heart disease. After statin therapy, the interpretation becomes more complicated. Statins can reduce cardiovascular events, slow growth of noncalcified plaque, and shift existing coronary plaque toward a denser, more calcified phenotype. Because the standard Agatston calcium score gives greater weight to dense calcium, the CAC number can rise even while plaque is becoming more stable. This is why current cardiovascular guidelines do not recommend repeating CAC scans to judge whether statin therapy is working.