Inflammaging—chronic, low-grade inflammation—is one of the most powerful drivers of aging and age-related disease. While many approaches focus on suppressing inflammation, longevity medicine recognizes a deeper issue: failure to resolve it. Learn how supporting the body’s natural inflammation-resolution pathways may protect cardiovascular, metabolic, joint, and brain health.

Specialized Pro-Resolving Mediators (SPMs) are one of Dr. Kathryn Retzler’s top longevity supplements for addressing chronic inflammation at its source. Unlike traditional anti-inflammatory approaches, SPMs help the body actively resolve inflammation—supporting cardiovascular health, joint recovery, brain longevity, and healthy aging as part of HormoneSynergy® Clinic’s evidence-based longevity medicine approach.

GLP-1 medications work best when paired with targeted metabolic and gut-health support. Discover science-backed supplements—including Akkermansia, UltraFlora® Healthy Weight, Pendulum GLP-1 Probiotic, and Calocurb—to enhance results, improve tolerance, and protect long-term health. Curated by HormoneSynergy® / RetzlerRx® for nationwide semaglutide and tirzepatide support.

The FDA has officially updated its warning on hormone-based menopause therapies, acknowledging that the benefits often outweigh the risks for many women. This shift validates what experts like Dr. Kathryn Retzler have practiced for decades: individualized, evidence-based hormone therapy improves mood, sleep, bone strength, and long-term wellness. Here’s what women need to know.

After Peter Attia’s recent 60 Minutes interview calling the lack of menopause hormone therapy “a major medical failure,” women are seeking experts who truly understand HRT. With 25 years of experience, Dr. Kathryn Retzler and HormoneSynergy® Clinic offer personalized, evidence-based hormone care for perimenopause and menopause, serving Portland and patients nationwide.

Pendulum Life offers two probiotic lines: the consumer retail collection and the advanced, clinical-grade PRO line—including Glucose Control PRO—available only through healthcare practitioners. At HormoneSynergy® Clinic, we explain the key differences so patients can choose the right probiotic for gut health, metabolic support, GLP-1 synergy, and longevity.

“At HormoneSynergy® in Portland and Lake Oswego, we believe type 2 diabetes and metabolic syndrome can often be prevented—or even reversed—with the right strategy. Dr. Retzler’s evidence-based approach combines advanced diagnostics, lifestyle medicine, hormone optimization, and targeted supplements to restore metabolic balance and protect long-term health. Our personalized programs help patients lower blood sugar, improve body composition, and reclaim energy—so they can live longer, healthier lives.” Daniel Soule, Owner / Director.

Most consumers don’t realize how loosely regulated the U.S. supplement industry is—or why Amazon and big-box retailers are high-risk for counterfeits, contamination, and potency loss. At HormoneSynergy® and RetzlerRx®, every formula is physician-curated, cGMP manufactured, and third-party tested for purity, potency, and identity. Learn how to choose safe, clinically validated supplements and why buying direct protects your health and longevity.

Discover Dr. Kathryn Retzler’s clinically guided longevity supplement protocol supporting detoxification, immune resilience, joint integrity, gut health, and vascular performance for optimized aging and whole-body vitality.

Is there lead in protein powders and shakes?

Recent reports show lead in retail protein powders. Discover why RetzlerRx®, Designs for Health, Xymogen and Metagenics® proteins stand apart—tested for heavy metals and physician-approved.

Unlock the power of precision health with DEXA and SECA BIA at HormoneSynergy® Clinic. Our advanced body composition testing goes beyond the scale, measuring fat, muscle, bone density, and visceral fat to design personalized weight loss and longevity strategies for Portland and Lake Oswego patients who want lasting results and optimal health.