Synergy Prostate Plus with Flowens® | Prostate & Urinary Health Support | RetzlerRx®

Synergy Prostate Plus with Flowens® – Prostate & Urinary Health Support*

RetzlerRx® Synergy Prostate Plus is a comprehensive men’s urinary and prostate support formula built around 500 mg of Flowens® cranberry fruit solids, the same daily amount evaluated in a randomized clinical trial in men with lower urinary tract symptoms.*

The formula combines Flowens® with beta-sitosterol, standardized saw palmetto extract, pygeum extract, zinc, and active vitamin B6 to support normal lower urinary tract function, urinary flow, prostate health, and prostate-related hormone metabolism.*

Why Flowens® Is the Centerpiece

Flowens® is a full-spectrum cranberry fruit powder developed specifically for urinary health.* Unlike a generic cranberry ingredient, Flowens® has been studied directly in men with lower urinary tract symptoms.

In a six-month randomized, double-blind, placebo-controlled trial involving 124 men over age 45, researchers compared 250 mg and 500 mg of Flowens® daily with placebo. Both Flowens® groups showed greater improvement in International Prostate Symptom Score (IPSS) than placebo, with the larger improvement seen at 500 mg. The 500 mg group also showed improvements from baseline in urinary-flow and post-void measurements.*

Synergy Prostate Plus provides 500 mg of Flowens® per two-softgel serving.

What Is in Synergy Prostate Plus?

• Flowens® Cranberry Fruit Solids – 500 mg – A clinically studied full-spectrum cranberry powder used to support normal lower urinary tract function and urinary comfort in men.*
• Saw Palmetto Extract – 320 mg – A standardized extract providing 85% free fatty acids. Saw palmetto has a long history of use in prostate formulas and is included here as one component of a broader multi-ingredient strategy.* Human evidence for saw palmetto by itself is mixed, which is why we do not view it as the entire prostate strategy.
• Beta-Sitosterol – 180 mg – A plant sterol with clinical evidence suggesting support for urinary symptom scores and urinary flow in men.* Research has not established that beta-sitosterol reduces prostate size or prevents progression of prostate disease.
• Pygeum Extract – 100 mg – An extract of Prunus africana traditionally used in men’s urinary formulas, with limited clinical evidence suggesting support for lower urinary tract symptoms and urinary function.*
• Zinc – 30 mg – Provided as TRAACS® zinc bisglycinate chelate. Zinc is an essential mineral involved in normal cellular, reproductive, and endocrine function.*
• Vitamin B6 – 10 mg – Supplied as pyridoxal 5'-phosphate, the active coenzyme form of vitamin B6, to support normal amino acid and cellular metabolism.*

A Formula, Not a Single-Ingredient Bet

Prostate supplements are often marketed around one ingredient. The evidence is more complicated than that.

Flowens® has direct randomized human research in men with lower urinary tract symptoms.* Beta-sitosterol also has evidence supporting urinary symptom and flow measures.* Saw palmetto has produced inconsistent results when studied by itself, while pygeum has more limited supportive evidence.*

That is why we view Synergy Prostate Plus as a multi-ingredient urinary and prostate support formula, rather than claiming that any single botanical solves prostate problems.*

Product Benefits

• Supports Healthy Urinary Flow* – Provides targeted nutrients and botanicals intended to support normal lower urinary tract function and urinary flow in men.*
• Supports Urinary Comfort and Frequency* – Flowens® has been clinically studied in men with lower urinary tract symptoms, including urinary storage and voiding concerns.*
• Supports Prostate Health* – Combines cranberry phytonutrients, plant sterols, standardized botanical extracts, zinc, and vitamin B6 for broad prostate nutritional support.*
• Supports Prostate-Related Hormone Metabolism* – The formula includes nutrients and botanicals involved in normal male endocrine and prostate physiology.*
• Provides Clinically Relevant Ingredient Amounts – The two-softgel serving provides 500 mg Flowens®, 320 mg standardized saw palmetto, 180 mg beta-sitosterol, and 100 mg pygeum.

Prostate Symptoms Still Deserve an Evaluation

A supplement can be part of a prostate-health strategy, but urinary symptoms should not automatically be assumed to be normal aging or benign prostate enlargement.

Men should seek medical evaluation for new or worsening urinary symptoms, blood in the urine, painful urination, fever or chills, recurrent urinary infections, inability to urinate, significant pelvic pain, an abnormal PSA, or symptoms that repeatedly disrupt sleep.

At HormoneSynergy®, prostate health is considered in the broader context of age, symptoms, PSA history, medications, metabolic health, hormone status, sleep, cardiovascular health, and appropriate urologic evaluation when indicated.

Suggested Use

Take two softgels daily, or as directed by your healthcare professional.

Individuals taking medications or being evaluated for prostate or urinary symptoms should discuss supplements with their healthcare professional.

Why RetzlerRx®?

RetzlerRx® supplements are selected and used within HormoneSynergy® Longevity Medicine, a physician-directed practice focused on evidence-based preventive longevity medicine.

We do not believe supplements replace good medical care. They should be used where they add something meaningful to a broader strategy that begins with appropriate evaluation, nutrition, exercise, sleep, metabolic health, medication review, and preventive care.

Clinical Resources

• Vidlar A, et al. Cranberry fruit powder (Flowens®) improves lower urinary tract symptoms in men: a double-blind, randomized, placebo-controlled study. World Journal of Urology.
• Wilt TJ, et al. Beta-sitosterol for the treatment of benign prostatic hyperplasia: a systematic review. BJU International.
• National Center for Complementary and Integrative Health: Saw Palmetto, Usefulness and Safety.
• HormoneSynergy®: Aging, Prostate Health, Longevity and BPH.

Frequently Asked Questions

What does Synergy Prostate Plus support?

Synergy Prostate Plus is designed to support normal lower urinary tract function, healthy urinary flow, urinary comfort, prostate health, and prostate-related hormone metabolism in men.*

What is Flowens®?

Flowens® is a full-spectrum cranberry fruit powder developed for urinary health.* It has been studied in randomized clinical research involving men over age 45 with lower urinary tract symptoms.* Synergy Prostate Plus provides 500 mg per two-softgel serving.

Has Flowens® actually been studied in men?

Yes. In a six-month randomized, double-blind, placebo-controlled study involving 124 men over age 45, both 250 mg and 500 mg daily doses of Flowens® were associated with greater improvements in International Prostate Symptom Score than placebo.* The 500 mg group also showed improvements from baseline in several urinary-flow measurements.*

Does Synergy Prostate Plus contain selenium?

No. The current formula contains vitamin B6, zinc, Flowens® cranberry fruit solids, saw palmetto extract, beta-sitosterol, and pygeum extract. Always refer to the current Supplement Facts panel for the most up-to-date formulation.

How much Flowens® is in each serving?

A two-softgel serving provides 500 mg of Flowens® cranberry fruit solids.

Does saw palmetto treat an enlarged prostate?

Saw palmetto is widely used in prostate supplements, but clinical studies of saw palmetto alone have produced inconsistent results. We do not consider it a substitute for evaluation or established treatment of benign prostatic hyperplasia. In Synergy Prostate Plus, saw palmetto is one part of a broader multi-ingredient prostate and urinary support formula.*

What is beta-sitosterol?

Beta-sitosterol is a naturally occurring plant sterol. Clinical trials have reported improvements in urinary symptom scores and urinary-flow measures in men using beta-sitosterol preparations, although long-term effects on prostate enlargement and disease progression remain uncertain.*

Who should have urinary symptoms evaluated rather than simply taking a supplement?

Men with new or worsening urinary symptoms, inability to urinate, blood in the urine, pain, fever, recurrent infection, an abnormal PSA, significant nighttime symptoms, or other concerning changes should seek appropriate medical evaluation.