Glutathione "The Mother of all Supplements" April 03 2017, 0 Comments

Coined “The Mother of All Antioxidants” by Mark Hyman, MD, glutathione is one of the hottest topics in both natural health and medical circles today. Pronounced “gloota-thigh-own,” nearly 117,000 peer-reviewed scientific articles have addressed this powerhouse molecule, and experts are now recognizing that an alarming rate of people are deficient because of:

  • Pre-mature aging
  • Infections
  • Chronic stress
  • Injuries
  • Environmental toxins
  • So-called “health foods”
  • Genetically modified foods
  • Artificial sweeteners
  • Overuse of antibiotics
  • And radiation therapy that is all too easily given to cancer patients today.

What Is Glutathione?

Reduced glutathione, commonly known as glutathione or GSH, is a tripeptide consisting of L-glutamine, L-cysteine, and glycine. It is ubiquitous in living systems. Glutathione bio-synthesis can be affected by biochemical individuality and/or dietary factors. Chronic oxidative stress can also deplete cellular glutathione. Glutathione is naturally synthesized from N-Acetyl Cysteine (NAC) in the human body.

Precursors to glutathione, such as whey protein, vitamin C, and glutamine, are also recommended to boost glutathione levels in the body; however, results are inconsistent. Biological individuality is such that not every body has equivalent ability to metabolize the precursor to raise glutathione.*

Why Not Give Pure Glutathione?

Unfortunately, most oral forms of glutathione are foul smelling, but more importantly,
the majority of an oral dose is oxidized before it can be absorbed and used by the cells. Two different formula's offer a unique preparation of glutathione that overcomes these usual limitations. The stability of S-acetylglutathione and Liposomal Glutathione through the intestinal wall and the plasma is well documented. Oral intake of S-acetyl glutathione increases total glutathione and percent-reduced glutathione. Percent-reduced glutathione is a very significant biomarker of health status.* [1-5]

The Two Most Absorbable Forms of Oral Glutathione*

HormoneSynergy® S-acetyl glutathione, a lipid-like compound, is taken up intact by chylomicrons in the gut. The acetyl bond is placed on its thiol group or sulfur group, which prevents oxidation and allows the molecule to pass diffusively into the cell after absorption in the gut. The bond is then cleaved by non-specific enzymes inside the cell. Acetylation prevents the breakdown of glutathione, and S-acetyl glutathione does not require energy expenditure to be cleaved to reduced glutathione once it crosses the cell wall.* [1-8] .

S-Acetyl Glutathione

HormoneSynergy® Liposomal Glutathione Synergy  provides 500 mg of pure glutathione and activated B vitamin cofactors delivered in phosphatidylcholine liposomes for optimal absorption and bioavailability support.*

Liposomal Glutathione

Antioxidant Activity

Glutathione functions extensively in tissues and organs throughout the body. It plays critical roles in protecting the body from oxidative stress, maintaining cellular functions, and supporting healthy immune function. [1,4] Many factors can increase cellular exposure to oxidative insult, and therefore increase cellular consumption of nutrients—such as glutathione—that provide antioxidant activity. This may result in a fierce cycle of oxidative stress and challenges to detoxification. Complete bio-transformation and protection from oxidative stress are important to maintaining cellular integrity and tissue health.* [2,5]