High-potency vitamin D3 with vitamins K1 and K2 as MK-7 for bone strength, healthy calcium metabolism, immune function and cardiovascular wellness.*
RetzlerRx® Vitamin D3 Plus K2 provides 5,000 IU of vitamin D3 per softgel together with vitamin K1 and 90 mcg of vitamin K2 as menaquinone-7, or MK-7. This once-daily formula is designed to support several connected aspects of bone, muscle, immune and calcium metabolism in one convenient softgel.*
Vitamin D3 supports intestinal calcium absorption, bone strength, normal muscle function and immune response. Vitamins K1 and K2 support vitamin K-dependent proteins involved in normal blood clotting, bone mineralization and calcium regulation throughout the body.*
Primary use: Bone health, calcium metabolism, immune function and cardiovascular wellness*
Vitamin D3: 5,000 IU as cholecalciferol per softgel
Vitamin K1: 20 mcg as phytonadione USP per softgel
Vitamin K2: 90 mcg as menaquinone-7, or MK-7, per softgel
Suggested use: 1 softgel daily, or as directed by your healthcare practitioner
Servings per container: 60
Typical bottle duration: Approximately 60 days
Dosage form: Softgel
What Is Vitamin D3 Plus K2?
Vitamin D3 Plus K2 is a combined fat-soluble vitamin formula designed to support calcium absorption and utilization. Vitamin D3 helps the body absorb calcium from the digestive tract, while vitamin K2 supports the activation of proteins involved in incorporating calcium into bone and maintaining normal calcium regulation in other tissues.*
This formula also provides vitamin K1 as phytonadione USP. Vitamin K1 is best known for supporting normal blood-clotting physiology, while vitamin K2 as MK-7 has a more specialized role in bone and calcium metabolism.*
Who May Consider This Formula?
RetzlerRx® Vitamin D3 Plus K2 may be appropriate for adults seeking nutritional support for:
- Bone strength and mineralization*
- Healthy calcium absorption and utilization*
- Normal immune function*
- Normal muscle function*
- Balanced calcium metabolism*
- Cardiovascular wellness as part of a broader prevention strategy*
- Nutritional support while using GLP-1 medications, when appropriate*
Vitamin D needs vary considerably. Laboratory testing, dietary intake, sun exposure, kidney function, medications and medical history may all affect whether 5,000 IU daily is appropriate.
Why This Formulation?
This formula combines vitamin D3 with both vitamin K1 and vitamin K2 as MK-7. Vitamin D3 is provided as cholecalciferol, the form commonly used to support vitamin D status and calcium absorption.*
Vitamin K2 is supplied as menaquinone-7, or MK-7, a longer-acting form commonly used in once-daily supplements. MK-7 supports vitamin K-dependent proteins involved in bone mineralization and normal calcium regulation.*
The softgel format provides a convenient once-daily serving of these fat-soluble nutrients. Each bottle contains 60 softgels, providing approximately a 60-day supply at the suggested use.
How Is It Different From Less Expensive Vitamin D Products?
Price alone does not determine whether a vitamin D supplement is appropriate. Many lower-cost products provide vitamin D3 alone, which may be suitable when vitamin K is not needed or is already supplied elsewhere.
RetzlerRx® Vitamin D3 Plus K2 provides 5,000 IU of vitamin D3 together with vitamin K1 and 90 mcg of vitamin K2 as MK-7. The more useful comparison is the amount and form of each vitamin, the serving size, the total number of servings and whether the combination fits the individual’s current supplement plan.
A combined formula is not automatically better for everyone. It is most useful when the included nutrients are appropriate and do not unnecessarily duplicate other products.
Suggested Use
Take 1 softgel daily, or as directed by your healthcare practitioner.
Because vitamins D3 and K are fat-soluble, this product is generally best taken with a meal containing dietary fat. Do not exceed the recommended dosage unless directed by your healthcare practitioner.
How Long Does One Bottle Last?
Each bottle contains 60 softgels. At the suggested use of 1 softgel daily, one bottle lasts approximately 60 days.
Important Cautions
Do not use this product without medical guidance if you take warfarin or another vitamin K-antagonist anticoagulant. Changes in vitamin K intake can affect anticoagulation control.
Consult a qualified healthcare professional before use if you are pregnant, breastfeeding, managing kidney disease, have elevated blood calcium, have a history of kidney stones or are taking prescription medication.
This formula provides 5,000 IU of vitamin D3 per serving, which is a high-potency amount. Long-term use is best individualized according to vitamin D status, total intake, medical history and clinician guidance.
Review all supplements for overlapping vitamin D or vitamin K. Excess vitamin D intake can contribute to elevated calcium levels. Keep out of reach of children and follow all label-specific storage instructions.
Quality and Dietary Information
- Non-GMO Project Verified
- Certified gluten-free
- Dairy-free
- No artificial colors
- Free from artificial preservatives
Why RetzlerRx®?
RetzlerRx® formulations are selected and developed for use within a physician-led Preventive Longevity Medicine practice. We prioritize meaningful ingredient forms and doses, responsible formulation, appropriate quality standards and clinical restraint.
Supplements are tools—not substitutes for diagnosis, medical treatment, resistance exercise, balanced nutrition, appropriate sun exposure or individualized laboratory assessment.
Frequently Asked Questions
How much vitamin D3 is in each softgel?
Each softgel provides 5,000 IU of vitamin D3 as cholecalciferol.
How much vitamin K is included?
Each softgel provides 20 mcg of vitamin K1 as phytonadione USP and 90 mcg of vitamin K2 as menaquinone-7, or MK-7.
Why combine vitamin D3 and vitamin K2?
Vitamin D3 supports calcium absorption, while vitamin K2 supports proteins involved in calcium regulation and bone mineralization. Their roles are complementary, although the appropriate amounts depend on diet, laboratory findings, medications and other supplements.*
What does vitamin D3 support?
Vitamin D3 supports calcium absorption, bone health, normal muscle function and normal immune function.*
Does vitamin K2 remove calcium from arteries?
Vitamin K2 should not be described as removing existing arterial calcium. It supports proteins involved in normal calcium regulation but is not a treatment for vascular calcification or cardiovascular disease.
Can I take this with another vitamin D supplement?
Possibly, but the total vitamin D amount should be reviewed first. This product already provides 5,000 IU per softgel, so combining it with other vitamin D products may create unnecessary or excessive intake.
Can I take this if I use warfarin?
Do not begin, stop or substantially change vitamin K intake without guidance from the clinician managing your anticoagulation therapy. Vitamin K1 and K2 can affect the action of warfarin and similar medications.
Should I take this with food?
Vitamins D3 and K are fat-soluble and are generally best taken with a meal containing dietary fat. Follow your healthcare practitioner’s guidance.
How long does one bottle last?
Each bottle contains 60 softgels. At 1 softgel daily, one bottle provides approximately a 60-day supply.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. The information provided is for educational purposes and is not a substitute for individualized medical advice.