Product Overview
Big Bold Health Immunity Chews combine 1 gram of HTB Activ™ sprouted Himalayan Tartary Buckwheat with zinc, magnesium, vitamin C, and vitamin D in a rich chocolate-flavored chew. They offer an easy way to increase daily polyphenol exposure while adding several foundational nutrients involved in normal immune function, energy metabolism, and cellular resilience.*
Best For
- Daily immune and nutritional support*
- Increasing whole-food polyphenol diversity*
- Adults who want HTB Activ™ without using another capsule
- Travel, work, and convenient on-the-go nutrition
- Supporting healthy energy metabolism with magnesium and zinc*
- People looking for a chocolate-flavored alternative to powders and capsules
A Different Kind of Daily Immune Support
Most immune-support supplements begin with isolated vitamins and minerals.
Immunity Chews start with food.
Each two-chew serving provides 1,000 mg of HTB Activ™, Big Bold Health's proprietary sprouted Himalayan Tartary Buckwheat ingredient, along with vitamin C, vitamin D, magnesium, and zinc.
The result is part functional food, part dietary supplement: a chocolate chew that combines a broad plant-polyphenol matrix with several familiar nutrients used in normal immune and metabolic physiology.*
It is also simply easy to use. There is no powder to mix, no shake to prepare, and no additional capsule to swallow.
1 Gram of HTB Activ™ Per Serving
Himalayan Tartary Buckwheat, Fagopyrum tataricum, is an ancient pseudocereal with a remarkably diverse phytochemical profile.
Big Bold Health developed HTB Activ™ from an heirloom Himalayan Tartary Buckwheat variety grown with U.S. farming partners. The seeds are sprouted, gently dried, and milled to preserve the broad spectrum of naturally occurring plant compounds produced during germination.
Big Bold Health reports that HTB Activ™ contains more than 100 naturally occurring polyphenols, including compounds associated with Tartary buckwheat such as rutin, quercetin, hesperidin, and a wider family of flavonoids and phenolic compounds.
Immunity Chews provide 1 gram of HTB Activ™ in every two-chew serving.
Why Sprouting Matters
A seed is biologically active long before it becomes a mature plant. Germination is the point when stored nutrients begin to mobilize and the young plant increases production of compounds involved in growth and environmental protection.
In Tartary buckwheat, sprouting changes the concentration and profile of polyphenols, flavonoids, phenolic acids, and other phytochemicals.
That is why HTB Activ™ is not simply ordinary buckwheat flour packed into a chew. Big Bold Health specifically uses sprouted Himalayan Tartary Buckwheat as the nutritional foundation of the product.
Polyphenol Diversity
Polyphenols are sometimes discussed as though they were one nutrient. They are actually a large and chemically diverse family of plant compounds.
Foods such as berries, cocoa, herbs, olives, vegetables, coffee, tea, and buckwheat contain different combinations of them. Those compounds can interact with cellular signaling, antioxidant-defense systems, vascular physiology, metabolism, and the intestinal microbiome.*
This diversity is one of the most interesting aspects of Himalayan Tartary Buckwheat. Rather than concentrating one isolated flavonoid, HTB Activ™ provides many plant compounds together within a food-derived matrix.
Learn more in our guide to Polyphenols, Immunometabolism, and Longevity Medicine.
Vitamin C
Each two-chew serving provides 10 mg of vitamin C.
Vitamin C contributes to normal immune function and cellular antioxidant defenses and is required for collagen synthesis and several enzymatic reactions throughout the body.*
The amount in Immunity Chews is intentionally modest. The product is built primarily around HTB Activ™ rather than functioning as a high-dose vitamin C supplement.
Vitamin D
Each serving provides 2.5 mcg (100 IU) of vitamin D3.
Vitamin D participates in normal immune signaling as well as bone, muscle, and calcium physiology.*
As with vitamin C, the amount here is nutritional rather than therapeutic. People using separate vitamin D supplementation can easily incorporate the 100 IU into their overall daily intake.
Zinc
Immunity Chews provide 4 mg of zinc per serving.
Zinc is required for the normal function of numerous enzymes and transcription factors and plays an important role in immune-cell development, protein synthesis, wound healing, and cellular metabolism.*
Four milligrams provides useful nutritional support without turning the chew into an unusually high-dose zinc product.
Magnesium
Each serving also contains 20 mg of magnesium.
Magnesium participates in hundreds of enzymatic reactions involving ATP production, muscle and nerve physiology, glucose metabolism, protein synthesis, and cellular signaling.*
The amount in Immunity Chews is supplemental support rather than a substitute for a dedicated magnesium formula when larger amounts are appropriate.
Cocoa + Himalayan Tartary Buckwheat
The chocolate format is more than a way to disguise the taste of a supplement.
Cocoa is itself a polyphenol-rich plant food, making it a natural partner for Himalayan Tartary Buckwheat. The flavor works particularly well with the toasted, nutty character of HTB.
Each serving contains 45 calories and 4 grams of total sugar, including 2 grams of added sugar. That is worth knowing, but it is also part of what makes the chews genuinely enjoyable enough to use consistently.
For many people, a supplement that actually gets taken every day has an advantage over the theoretically perfect product sitting untouched in a cabinet.
The Gut-Immune Connection
A large part of immune biology takes place at the intestinal interface.
Food compounds, intestinal microbes, microbial metabolites, immune cells, and the gut barrier continually communicate with one another. Polyphenols are particularly interesting because intestinal microorganisms help metabolize many of them, while those compounds and their metabolites can in turn influence the microbial environment.
HTB Activ™ therefore fits naturally into a broader conversation about dietary plant diversity and the microbiome rather than functioning only as an isolated antioxidant ingredient.
Explore that system in our Gut Health, Microbiome, and Longevity Medicine resource.
Food, Immunity, and Metabolism Are Connected
Immune cells require energy. Metabolism influences immune-cell behavior. The microbiome produces metabolites that communicate with both systems. Sleep, body composition, glucose regulation, physical activity, and dietary quality influence the environment in which those signals occur.
This intersection is increasingly described as immunometabolism.
It helps explain why an immune-support strategy built around food quality and plant diversity makes biological sense alongside adequate micronutrients.
For more on that relationship, see What Is Immunometabolism?
Research on HTB Activ™
Himalayan Tartary Buckwheat has an expanding research literature examining its flavonoids, polyphenols, sprouting biology, phytochemical composition, and interaction with metabolic and cellular pathways.
Big Bold Health has also completed a large randomized, placebo-controlled human trial of HTB Activ™ involving approximately 850 participants.
As of August 2026, results from that trial have not yet been published and Big Bold Health reports that findings are expected by the end of 2026.
Until those results are available, the strongest case for Immunity Chews remains the composition itself: a convenient serving of sprouted Himalayan Tartary Buckwheat with a broad whole-food polyphenol profile plus several well-established nutritional cofactors for normal immune physiology.*
How to Use Immunity Chews
Adults take 2 chews daily, with or without food, or use as directed by a healthcare professional.
Each jar contains 60 chews, providing approximately 30 servings.
Product Features
- 1,000 mg HTB Activ™ per serving
- More than 100 naturally occurring polyphenols in HTB Activ™
- Vitamin C
- Vitamin D3
- Magnesium
- Zinc
- Chocolate-flavored chew
- Gluten-free
- Grain-free
- Vegetarian
- Non-GMO Project Verified
- Regeneratively farmed HTB
- Ancient heirloom Himalayan Tartary Buckwheat seed
- Minimally processed
- USA-produced
Formerly HTB Immune Energy Chews
If the packaging or product name looks familiar, there is a reason.
Big Bold Health previously sold this product as HTB Immune Energy Chews. It is now called Immunity Chews. Big Bold Health identifies it as the same formula, so older packaging and product references may still use the previous name.
The HormoneSynergy® Perspective
There is a lot to like about Immunity Chews.
The central ingredient is not another megadose vitamin. It is a gram of sprouted Himalayan Tartary Buckwheat delivering a broad food-derived polyphenol matrix.
Vitamin C, vitamin D, zinc, and magnesium then add familiar nutritional support around that foundation.*
And the chocolate chew format solves a practical problem that supplement discussions often ignore: convenience and adherence matter.
For someone who wants an easy daily source of HTB Activ™ and would rather eat a small chocolate chew than add another capsule or powder to the routine, Immunity Chews are an appealing option.
Frequently Asked Questions
What are Big Bold Health Immunity Chews?
Immunity Chews are chocolate-flavored chews combining HTB Activ™ sprouted Himalayan Tartary Buckwheat with vitamin C, vitamin D, magnesium, and zinc for daily polyphenol and immune support.*
How much HTB Activ™ is in each serving?
Two chews provide 1,000 mg, or 1 gram, of HTB Activ™.
What is HTB Activ™?
HTB Activ™ is Big Bold Health's proprietary sprouted Himalayan Tartary Buckwheat ingredient. It is grown with U.S. farming partners, sprouted, gently dried, and milled, and contains a diverse spectrum of naturally occurring plant polyphenols.
How many polyphenols are in HTB Activ™?
Big Bold Health reports that HTB Activ™ contains more than 100 naturally occurring polyphenols, including compounds associated with Tartary buckwheat such as rutin, quercetin, and hesperidin.
What vitamins and minerals are in Immunity Chews?
Each two-chew serving provides 10 mg vitamin C, 2.5 mcg (100 IU) vitamin D3, 20 mg magnesium, and 4 mg zinc.
How many calories and how much sugar are in a serving?
Two chews provide approximately 45 calories, 4 grams of total sugar, and 2 grams of added sugar.
Are Immunity Chews gluten-free?
Yes. Big Bold Health currently identifies Immunity Chews as gluten-free and grain-free.
Are Immunity Chews vegetarian?
Yes. The current manufacturer information identifies the product as vegetarian.
Is Himalayan Tartary Buckwheat actually wheat?
No. Despite the name, buckwheat is not botanically related to wheat. It is a pseudocereal related to plants such as rhubarb and sorrel.
Were Immunity Chews previously called HTB Immune Energy Chews?
Yes. Big Bold Health renamed HTB Immune Energy Chews as Immunity Chews and identifies the current product as the same formula.
How should I take Immunity Chews?
Adults take two chews daily, with or without food, or use as directed by a healthcare professional.