RetzlerRx® Estro Protect DIM combines diindolylmethane (DIM) and indole-3-carbinol (I3C), compounds associated with cruciferous vegetables, for targeted nutritional support of normal estrogen metabolism in women and men.*
Estrogen balance involves more than the amount of hormone the body produces. Estrogens must also be metabolized, conjugated and eliminated through coordinated activity involving the liver, gastrointestinal tract and other tissues. DIM and I3C may be used when additional nutritional support for these normal pathways is appropriate.*
Why Estrogen Metabolism Matters
Estrogen is essential to normal physiology in both women and men. After estrogen has carried out its biological functions, the body converts it into different metabolites that can be further processed and eliminated.
Diet, alcohol intake, medications, liver and bowel function, body composition and individual physiology can all influence this process. A supplement does not replace attention to those factors, but it may provide targeted support within a broader hormone-health plan.*
For a more complete discussion, read Hormones, Weight Loss and Detoxification: Where Sulforaphane Fits.
Key Features
- DIM and I3C: Combines two compounds associated with cruciferous vegetables in one formula.
- Estrogen-metabolism support: Supports the body’s normal processing of estrogen and its metabolites.*
- For women and men: May be considered when targeted nutritional support for estrogen metabolism is appropriate.*
- Practitioner-grade formulation: Designed for use as part of an individualized nutrition or hormone-health plan.
DIM and Indole-3-Carbinol
Indole-3-carbinol is formed from glucobrassicin, a glucosinolate found in vegetables such as broccoli, cabbage, cauliflower, kale and Brussels sprouts. DIM is one of the compounds that can form from I3C after cruciferous vegetables are eaten.
A supplement provides these compounds in a consistent form, but it does not reproduce the fiber, vitamins, minerals and broader mixture of plant compounds found in whole vegetables. Estro Protect DIM is best viewed as targeted nutritional support rather than a replacement for a varied diet.
Who May Consider Estro Protect DIM?
Estro Protect DIM may be considered by adults seeking nutritional support for normal estrogen metabolism as part of a broader hormone or longevity plan.* Individual needs vary, and the formula should not be used simply because someone assumes that estrogen is “too high.” Symptoms attributed to estrogen can have several causes and may require appropriate clinical evaluation.
Suggested Use
Use as directed on the product label or according to the guidance of your healthcare professional.
Important Considerations
Discuss this product with an appropriate healthcare professional if you are pregnant or breastfeeding, use hormonal contraception or hormone therapy, take prescription medication, have a hormone-sensitive medical condition or are undergoing treatment for cancer.
DIM and I3C supplements are not substitutes for breast, cervical, prostate or other age-appropriate medical screening. They should not be presented or used as treatments for cancer or other diseases.
Supplements in Support. Healthspan at the Core.
At HormoneSynergy®, supplements are selected to address a defined nutritional goal within a larger health plan. Nutrition, fiber intake, bowel regularity, sleep, exercise, alcohol intake, body composition and appropriate medical assessment remain the foundation.
Explore the RetzlerRx® Longevity Supplement Guide or visit the HormoneSynergy® Longevity Medicine Resource Library for additional education on hormones, metabolism and healthy aging.
Practitioner-grade supplement available through HormoneSynergy® Longevity Medicine in Lake Oswego, Oregon, with nationwide shipping.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Frequently Asked Questions
What are DIM and indole-3-carbinol?
Indole-3-carbinol is formed from a glucosinolate found in cruciferous vegetables. DIM is one of the compounds that can form from I3C. Both are used in supplements intended to support normal estrogen-metabolism pathways.*
Is Estro Protect DIM intended only for women?
No. Women and men both produce and metabolize estrogen. Estro Protect DIM may be considered for either when targeted nutritional support is appropriate.*
Does DIM lower estrogen?
DIM should not be described simply as an estrogen-lowering supplement. It is used to support normal estrogen-metabolism pathways.* Its effects and appropriateness can vary according to hormone status, medications and individual physiology.
Can Estro Protect DIM be used with hormone therapy?
Possibly, but it should not be added automatically. Anyone using estrogen, testosterone, hormonal contraception or another hormone-related medication should discuss DIM and I3C with the healthcare professional managing that treatment.
Does this replace eating cruciferous vegetables?
No. Broccoli, cabbage, cauliflower, kale and Brussels sprouts provide fiber and many nutrients that are not reproduced by a DIM and I3C supplement.