At HormoneSynergy® Clinic and RetzlerRx®, we evaluate probiotics through a longevity-focused, clinical lens. As a nationally trusted U.S. longevity medicine clinic, we work with patients across the country who want evidence-based, clinician-guided solutions for gut health, metabolic health, and weight optimization. Pendulum Life is one of the few companies that produces strain-specific, clinically validated probiotics designed to support gut function, metabolic outcomes, GLP-1 pathways, and overall healthspan.

But many patients don’t realize Pendulum offers two different product lines:

1️⃣ Retail Line – available to the public
2️⃣ PRO Line – clinician-only, higher-potency formulations available exclusively through healthcare practitioners, including HormoneSynergy® Clinic

Here’s exactly how they differ—and which is better depending on your goals.

Pendulum Retail Probiotics (Public)

The retail collection includes:

• Akkermansia

• Metabolic Daily

• Glucose Control (retail strength)

• Polyphenol Booster

Best for:
✔ General gut health
✔ Entry-level metabolic support
✔ Consumers seeking a high-quality starting point

Limitations:

• Lower potency

• Fewer specialized strains

• Not the same as clinical research dosing

Pendulum PRO: Practitioner-Only Formulations for U.S. Patients Nationwide

As a U.S. clinician-dispensed line, Pendulum PRO offers significantly stronger, more targeted microbiome support. These formulas are accessible only through licensed practitioners like HormoneSynergy® Clinic and provide the dosing and strain specificity used in clinical research.

1. Akkermansia 500 PRO

Higher potency for mucosal repair, gut barrier integrity, and metabolic support.

2. Metabolic Daily PRO

Supports GLP-1 activity, post-meal glucose response, SCFA production, and metabolic flexibility.

3. GLP-1 Probiotic PRO

Pendulum GLP-1 Probiotic Pro is formulated with beneficial bacterial strains that naturally increase GLP-1*, a satiety hormone that helps maintain a healthy weight.

4. Glucose Control PRO

Clinician-only metabolic probiotic targeting:

• Insulin sensitivity

• Glucose response

• GLP-1 pathway modulation

• Metabolic dysfunction

• PCOS, prediabetes, and insulin resistance

5. Professional Powdered Strain Formats

Offered to healthcare practitioners for custom protocols.

6. Proprietary R&D Clinical Blends

Advanced strains and SCFA-support blends not available to the public.

Retail vs. PRO: Side-by-Side Comparison

Why HormoneSynergy® Clinic Recommends Pendulum PRO

As a functional and longevity medicine practice serving patients nationwide across the United States, we rely on products that deliver measurable outcomes. Pendulum PRO formulations allow us to:

• Personalize metabolic support

• Strengthen the gut barrier

• Improve glucose regulation

• Support GLP-1 weight loss programs

• Enhance microbiome diversity

• Optimize long-term healthspan

For many patients, PRO formulations outperform retail options.

Where to Purchase Pendulum PRO

HormoneSynergy® Clinic provides access to the full clinician-only Pendulum PRO line, including:

• Akkermansia 500 PRO

• GLP-1 Probiotic PRO

• Glucose Control PRO

• Metabolic Daily PRO

• Additional practitioner formulas

Click Here to Support gut health, metabolic balance, and microbiome diversity with the Pendulum® Life PRO Supplement Collection. 

Disclaimer

For educational purposes only. Not intended to diagnose or treat disease. These statements have not been evaluated by the FDA.

HormoneSynergy® Clinic proudly supports patients nationwide with evidence-based, physician-directed probiotics and longevity medicine solutions delivered throughout the United States.